M-Audio Radium 49 is an "end of line" product, meaning official driver support has ceased for recent macOS versions. If you are using a modern Mac (macOS Catalina, Big Sur, Monterey, Ventura, or Sonoma), it will likely not work via a direct USB connection because it is not class-compliant and requires legacy drivers. Apple Discussions Compatibility Status Officially Supported: Up to macOS 10.8.5 (Mountain Lion). Last Known Working (with Drivers): Some users have successfully used the MIDI USB Driver v3.5.3 on macOS Mojave (10.14) or Yosemite (10.10.3). Incompatible:
| macOS Version | Official Driver Available | Functionality Level | Recommendation | |---------------|--------------------------|---------------------|------------------| | 10.5 – 10.13 (Leopard–High Sierra) | Yes (Radium49_OSX_2.2.2) | Full | Use legacy driver | | 10.14 (Mojave) | Partial (32-bit deprecation) | Limited | Not recommended | | 10.15 (Catalina) – 14.x (Sonoma) | No | Class-compliant only | Use third-party tools | m-audio radium 49 driver mac
Version 3.5.3 is the most recent release, originally designed for older versions of OS X. M-Audio Radium 49 is an "end of line"
When connected via USB, the Radium 49 is automatically recognized by macOS’s native USB MIDI driver. You will see the device in: Last Known Working (with Drivers): Some users have
If you are on an older Mac and require the driver for full functionality:
The Radium 49 is not "class-compliant," meaning it requires a specific driver to communicate via USB. Official support effectively ended after .
